I assume you live in Dyer, IN., if so, This will be a long driving day for you.
Look at the weather forecast for the area of FL you intend to visit before leaving home. For instance the high today in Miami is forecast to be 34°F, Tampa 32°, Jacksonville 28°.
That is usually short-lived though.
Our MH has heated tanks and plumbing. I remain winterized until I reach I65 @ exit 354, Athens AL, and stay at
Northgate RV park. It's very quiet and peaceful. It's also convenient, as it's on US31, about 1 mile from that exit.
This year is exceptional though, you might need to stay winterized until you reach an area where lows are 32°.
Best of luck, and I hope the weather improves South of the Mason Dixon line.
Edit: Closely study the route through Nashville TN. It is very heavily congested most all day, exits close together. IMO it's just bad as driving through Atlanta GA. now.