My 2019 2108DS has the water heater bypass valves behind the lower panel of the bathroom sink. Remove the 4 screws that hold the panel and pull it off and you'll see something like this (unless it has changed in newer models). As is usual with these valves, when the handle is in-line with the pipe it lets water through, and if the handle is crosswise of the pipe it won't let water through.
The point of the bypass is so you don't fill the water heater tank with anti-freeze. So flush the system first before turning these knobs 90 degrees, otherwise you'll just flush anti-freeze into the water heater. If you do that by accident, you'll just need to flush it more.
The water pump bypass valves under the kitchen sink floor panel look like this in my rig. I think these have moved a little in newer models, but their function probably remains the same.
The big red arrow in that last photo is the antifreeze pigtail as mentioned by @Zorak9. The valve to the left that is partly hidden is for the pigtail which loops along the floor. Sorry you can't see it all. The other valve controls input flow from the hose that's going down under the floor into the freshwater tank. You'll need that open as it says. The hose coming out of the pump at the front of the photo is the output from the pump and it snakes off to the right to feed the rest of the plumbing in the rig.
My low point drains are under a little box on the floor of the bathroom closet. These have probably moved in newer models. As @Zorak9 says, these are odd. The little T-handle is pulled up, or pushed down. You can turn them all you want, but that doesn't do anything.
If you forget the low point drains and they are open, you'll just start dumping water on the ground outside when you turn the water on. No big deal...just close them.
I have a standard atwood/dometic 6 gal water heater. Here's what it looks like and you can see the drain plug that will need to be in place. The red arrow points to it. And, fyi, there is no anode rod for those looking to find it as this tank is aluminum and doesn't have a rust issue that would need an anode rod.
Hope that helps.