I own a 2016 22R, bought last August and now have about 9000 trouble free miles on the E350 chaise and v8. We live out west, mountain country, and get about 9mpg and I also tow a MKZ behind it sometimes and it towed it just fine, from Seattle to San Diego and back. Its just the two of us, no kids, no pets, no troubles. Mine is the entry level model and paid about $54,000 for it new with no trade in.
2016 Minnie Winnie 22R; 2012 Lincoln MKZ toad;2013 F150 EcoBoost; 1st RV 2006 Wildwood 5er Bunkhouse; 2nd RV used 2001 Itasca Suncrusier