When I do my due diligence for route and campground planning, I routinely compare these products against each other for consensus:
-CoPilot Live 9
-DeLorme Street Atlas USA 2006 Plus
-Microsoft Streets & Trips 2006
-Trailer Life Campground Navigator 2006
-occasionally I use maps.google.com
CoPilot Live: This is my preferred product for active navigation due to it being extremely easy to use and I love the nav presentation. I can tell it to calculate routes with factoring in propane (tunnels) and height (>12'6") restrictions. Its primary weakness is the POI database - it is incomplete and sometimes just plain wrong. I always verify a POI and calculated route before I use it for navigation. It doesn't have many streets in Alaska or Canada in the database.
DeLorme: Not being a regular user of DeLorme, I find the user interface horribly complex, un-intuitive and difficult to use. The POI database is marginally better than CoPilot, not that's not saying much. This is my least favorite product - the only reason I have it is because it was given to me.
MS Streets/Trips: Really great user interface, amazing amount of detail and accuracy of detail (I used it yesterday for navigation here in British Columbia and it was spot-on), by far the most complete and accurate POI database by a huge margin over the other products. A
MAJOR limitation of the product is that it will not do real-time routing, i.e., if you make a wrong turn it simply says "off route", it will not provide ETA either. This is the primary reason why I practically never use it for active navigation.
Trailer Life: Really great for campground planning but I have not used it for active navigation. The interface seems to be fairly crude.
Maps.google: Usually pretty accurate when I am cross-checking campground locations but it would have placed me several miles away in our present campground. First serious error I have seen with this.
It's a darn shame that CoPilot and S&T can't be melded somehow!
Just my experiences...